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A comparative study of three-dimensional airway changes after fibula flap reconstruction for benign and malignant tumours in the anterior mandible

  • Author Footnotes
    1 Wen Du and Guolin Liu are co-first authors.
    W. Du
    Footnotes
    1 Wen Du and Guolin Liu are co-first authors.
    Affiliations
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China
    Search for articles by this author
  • Author Footnotes
    1 Wen Du and Guolin Liu are co-first authors.
    G. Liu
    Footnotes
    1 Wen Du and Guolin Liu are co-first authors.
    Affiliations
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China

    Department of Stomatology, Liangxiang Hospital of Beijing Fangshan District, Beijing, China
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  • W. Zhang
    Affiliations
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China
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  • N. Zhao
    Affiliations
    Institute of Quantitative Economics, School of Economics, Nankai University, Tianjin, China
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  • Y. Shi
    Affiliations
    Department of Stomatology, Liangxiang Hospital of Beijing Fangshan District, Beijing, China
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  • X. Peng
    Correspondence
    Correspondence to: Peking University School and Hospital of Stomatology, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 10081, China.
    Affiliations
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China
    Search for articles by this author
  • Author Footnotes
    1 Wen Du and Guolin Liu are co-first authors.
Published:December 27, 2022DOI:https://doi.org/10.1016/j.ijom.2022.12.007

      Abstract

      Surgical treatment of tumours in the anterior mandible and surrounding tissues may result in defects which can be restored by a fibula free flap. The upper airway may change during this process. The purpose of this retrospective study was to evaluate upper airway changes after fibula free flap reconstruction. A total of 37 patients who underwent anterior mandibulectomy and fibula free flap reconstruction between 2012 and 2020 were recruited. Patients with benign and malignant tumours involving the anterior mandible were included. Spiral computed tomography was performed 1 week preoperatively, 1 week postoperatively, and at> 1 year (range 12–23 months) after surgery. Cross-sectional areas and volumes of the upper airway were measured. Data were analysed by two-way analysis of variance. The upper airway in the malignant tumour group showed an increasing trend, especially at the soft palate and tongue base levels (P < 0.01). In the benign tumour group, the upper airway showed no significant changes. The location of the minimum cross-sectional area moved downwards in both groups, and the area increased in the malignant tumour group during long-term follow-up. Upper airway obstruction is less likely to occur in the long term after surgical resection of anterior mandible malignancies and fibula free flap reconstruction.

      Keywords

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