Abstract
Previous studies have lacked a clear anatomical and functional definition of glossectomy
for tongue cancer adjacent to or crossing the midline (TCML). The aim of this study
was to provide a novel surgical approach based on anatomical unit resection surgery
to treat TCML. A total of 120 patients with TCML who had undergone radical surgery
were recruited retrospectively into the study. The patients who were treated with
compartment surgery formed the control group; those treated with anatomical unit resection
surgery formed the experimental group. The TCML was classified into cancer adjacent
to the midline, cancer invading but not breaching the contralateral musculus verticalis
linguae–genioglossus complex (MGC), and cancer breaching the contralateral MGC. No
significant difference in the overall survival rate was found between the experimental
and control groups overall (P = 0.853) or by TCML classification. In patients with cancer adjacent to the midline,
the swallowing score (P = 0.040) and cosmetic outcome (P = 0.015) were significantly better in the experimental group than in the control
group. For patients with cancer invading but not breaching the contralateral MGC,
the speech intelligibility score (P = 0.001), swallowing score (P = 0.002), and cosmetic outcome (P = 0.037) were significantly better in the experimental group than in the control
group. Anatomical unit resection surgery was found to provide a precise surgical treatment
to address tongue cancer adjacent to or crossing the midline and maximally maintain
tongue tissue and function.
Keywords
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Article info
Publication history
Published online: December 07, 2022
Accepted:
November 25,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
