Advertisement

Comparison of quality of life and psychological distress in patients with tongue cancer undergoing a total/subtotal glossectomy or extended hemiglossectomy and free flap transfer: a prospective evaluation

Published:December 02, 2022DOI:https://doi.org/10.1016/j.ijom.2022.11.010

      Abstract

      The aim of this study was to assess changes in the quality of life and psychological distress of patients with tongue cancer undergoing total/subtotal glossectomy (TG) or extended hemiglossectomy (HG) and free flap transfer. Differences between the two groups were compared using the Short Form 8-Item Health Survey (SF-8) and Hospital Anxiety and Depression Scale (HADS). Of the 43 patients with tongue cancer, 24 (56%) underwent TG and 19 (44%) underwent HG. The general health and social functioning scores in the SF-8 and depression in the HADS were significantly worse in the TG group than in the HG group at 12 months after surgery, indicating that patients in the TG group may experience social isolation and psychological distress, and have difficulty in employability even 12 months after surgery. In contrast, all items of the SF-8 in the HG group were nearly equal to those in the general population. Due to the extensive psychological impact on patients with tongue cancer who are planned for an extended resection, curative surgery with free flap transfer and multidisciplinary psychiatric support are essential to improve quality of life and manage psychological distress.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to International Journal of Oral and Maxillofacial Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Campana J.P.
        • Meyers A.D.
        The surgical management of oral cancer.
        Otolaryngol Clin N Am. 2006; 39: 331-348
        • Hamman J.
        • Howe C.L.
        • Borgstrom M.
        • Baker A.
        • Wang S.J.
        • Bearelly S.
        Impact of close margins in head and neck mucosal squamous cell carcinoma: a systematic review.
        Laryngoscope. 2022; 132: 307-321
        • Barber B.
        • Dergousoff J.
        • Slater L.
        • Harris J.
        • O’Connell D.
        • El-Hakim H.
        • Biron V.L.
        • Mitchell N.
        • Seikaly H.
        Depression and survival in patients with head and neck cancer: a systematic review.
        JAMA Otolaryngol Head Neck Surg. 2016; 142: 284-288
        • Lam L.
        • Samman N.
        Speech and swallowing following tongue cancer surgery and free flap reconstruction—a systematic review.
        Oral Oncol. 2013; 49: 507-524
        • Yue J.
        • Zhuo S.
        • Zhang H.
        • Liu X.
        • Zhang W.
        Long-term quality of life measured by the University of Washington QoL questionnaire (version 4) in patients with oral cancer treated with or without reconstruction with a microvascular free flap.
        Br J Oral Maxillofac Surg. 2018; 56: 475-481
        • Vincent L.
        • Kohlert S.
        • Lee T.S.
        • Inman J.
        • Ducic Y.
        Free-flap reconstruction of the tongue.
        Semin Plast Surg. 2019; 33: 38-45
        • Costa Bandeira A.K.
        • Azevedo E.H.
        • Vartanian J.G.
        • Nishimoto I.N.
        • Kowalski L.P.
        • Carrara-de Angelis E.
        Quality of life related to swallowing after tongue cancer treatment.
        Dysphagia. 2008; 23: 183-192
        • Ihara Y.
        • Tashimo Y.
        • Nozue S.
        • Iizumi Y.
        • Fukunishi Y.
        • Saito Y.
        • Shimane T.
        • Takahashi K.
        Changes in oral function and quality of life in tongue cancer patients based on resected area.
        Asian Pac J Cancer Prev. 2021; 22: 2549-2557
        • Ansarin M.
        • Bruschini R.
        • Navach V.
        • Giugliano G.
        • Calabrese L.
        • Chiesa F.
        • Medina J.E.
        • Kowalski L.P.
        • Shah J.P.
        Classification of glossectomies: proposal for tongue cancer resections.
        Head Neck. 2019; 41: 821-827
        • Heo Y.H.
        • Yagi S.
        • Toriyama K.
        • Takanari K.
        • Fujimoto Y.
        • Nishio N.
        • Fujii M.
        • Saito K.
        • Takahashi M.
        • Kamei Y.
        Relationship between BMI and postoperative complications with free flap in anterolateral craniofacial reconstruction.
        Plast Reconstr Surg Glob Open. 2016; 4e636
        • Nishio N.
        • Fujii M.
        • Hayashi Y.
        • Hiramatsu M.
        • Maruo T.
        • Iwami K.
        • Kamei Y.
        • Yagi S.
        • Takanari K.
        • Fujimoto Y.
        Preoperative surgical simulation and validation of the line of resection in anterolateral craniofacial resection of advanced sinonasal sinus carcinoma.
        Head Neck. 2017; 39: 512-519
        • Adachi Y.
        • Kimura H.
        • Sato N.
        • Nagashima W.
        • Nakamura K.
        • Aleksic B.
        • Yoshida K.
        • Fujimoto Y.
        • Nakashima T.
        • Ozaki N.
        Preoperative level of depression is a predictor of postoperative levels of depression in patients with head and neck cancer.
        Jpn J Clin Oncol. 2014; 44: 311-317
        • American Psychiatric Association
        Diagnostic and Statistical Manual of Mental Disorders.
        Fifth edition. American Psychiatric Publishing, Washington, DC2013
        • Kugaya A.
        • Akechi T.
        • Okuyama T.
        • Okamura H.
        • Uchitomi Y.
        Screening for psychological distress in Japanese cancer patients.
        Jpn J Clin Oncol. 1998; 28: 333-338
        • Zigmond A.S.
        • Snaith R.P.
        The hospital anxiety and depression scale.
        Acta Psychiatr Scand. 1983; 67: 361-370
        • Mukoyama N.
        • Nishio N.
        • Kimura H.
        • Kishi S.
        • Tokura T.
        • Kimura H.
        • Hiramatsu M.
        • Maruo T.
        • Tsuzuki H.
        • Fujii M.
        • Iwami K.
        • Takanari K.
        • Kamei Y.
        • Ozaki N.
        • Sone M.
        • Fujimoto Y.
        Prospective evaluation of health-related quality of life in patients undergoing anterolateral craniofacial resection with orbital exenteration.
        J Neurol Surg B Skull Base. 2020; 81: 585-593
        • Swigris J.J.
        • Brown K.K.
        • Behr J.
        • Bois R.M.
        • King T.E.
        • Raghu G.
        • Wamboldt F.S.
        The SF-36 and SGRQ: validity and first look at minimum important differences in IPF.
        Respir Med. 2010; 104: 296-304
        • Manrique O.J.
        • Leland H.A.
        • Langevin C.J.
        • Wong A.
        • Carey J.N.
        • Ciudad P.
        • Chen H.C.
        • Patel K.M.
        Optimizing outcomes following total and subtotal tongue reconstruction: a systematic review of the contemporary literature.
        J Reconstr Microsurg. 2017; 33: 103-111
        • Kanatas A.N.
        • Rogers S.N.
        A systematic review of patient self-completed questionnaires suitable for oral and maxillofacial surgery.
        Br J Oral Maxillofac Surg. 2010; 48: 579-590
        • Rogers S.N.
        • Lowe D.
        • Brown J.S.
        • Vaughan E.D.
        The University of Washington head and neck cancer measure as a predictor of outcome following primary surgery for oral cancer.
        Head Neck. 1999; 21: 394-401
        • Rogers S.N.
        • Lowe D.
        • Fisher S.E.
        • Brown J.S.
        • Vaughan E.D.
        Health-related quality of life and clinical function after primary surgery for oral cancer.
        Br J Oral Maxillofac Surg. 2002; 40: 11-18
        • Ture M.
        • Aeschlimann A.
        • Renner C.
        • Schnyder U.
        • Zerkiebel N.
        • Perseus J.
        • Barth J.
        • Bredell M.
        • Soelch C.M.
        • Walt H.
        • Jenewein J.
        Short-term effectiveness of impairment cancer rehabilitation: a longitudinal controlled cohort study.
        J Cancer. 2017; 8: 1717-1725
        • Yun Y.H.
        • Sim J.A.
        • Jung J.Y.
        • Noh D.Y.
        • Lee E.S.
        • Kim Y.W.
        • Oh J.H.
        • Ro J.S.
        • Park S.Y.
        • Park S.J.
        • Cho K.H.
        • Chang Y.J.
        • Bae Y.M.
        • Kim S.Y.
        • Jung K.H.
        • Zo Z.I.
        • Lim J.Y.
        • Lee S.N.
        The association of self-leadership, health behaviors, and posttraumatic growth with health-related quality of life in patients with cancer.
        Psychooncology. 2014; 23: 1423-1430
        • Jörngarden A.
        • Mattsson E.
        • Essen L.
        Health-related quality of life, anxiety and depression among adolescents and young adults with cancer: a prospective longitudinal study.
        Eur J Cancer. 2007; 43: 1952-1958
        • Harding S.A.
        • Hodder S.C.
        • Courtney D.J.
        • Bryson P.J.
        Impact of perioperative hyperbaric oxygen therapy on the quality of life of maxillofacial patients who undergo surgery in irradiated fields.
        Int J Oral Maxillofac Surg. 2008; 37: 617-624
        • Miyoshi M.
        • Fukuhara T.
        • Kataoka H.
        • Hagino H.
        Relationship between quality of life instruments and phonatory function in tracheoesophageal speech with voice prosthesis.
        Int J Clin Oncol. 2016; 21: 402-408
        • Markey J.D.
        • Morrel W.G.
        • Wang S.J.
        • Ryan W.R.
        The effect of submandibular gland preservation during level 1B neck dissection on postoperative xerostomia.
        Auris Nasus Larynx. 2018; 45: 123-127
        • Leonhardt F.D.
        • Quon H.
        • Abrahao M.
        • O’Malley Jr, B.W.
        • Weinstein G.S.
        Transoral robotic surgery for oropharyngeal carcinoma and its impact on patient-reported quality of life and function.
        Head Neck. 2012; 34: 146-154
        • Nemade H.
        • Chaitanya S.A.
        • Kumar S.
        • Rao A.A.K.
        • Rao T.S.
        • Oncological S.L.
        outcomes of total glossectomy procedure for advanced tongue cancer: a single-centre experience.
        Int J Oral Maxillofac Surg. 2022; 51: 152-158
        • Huang Z.S.
        • Chen W.L.
        • Huang Z.Q.
        • Yang Z.H.
        Dysphagia in tongue cancer patients before and after surgery.
        J Oral Maxillofac Surg. 2016; 74: 2067-2072
        • Kung L.Y.
        • Li T.I.
        • Chung C.H.
        • Lee S.P.
        • Chen G.S.
        • Chien W.C.
        • Tzeng N.S.
        Risk of depression in patients with oral cancer: a nationwide cohort study in Taiwan.
        Sci Rep. 2021; 1123524
        • Salibian A.H.
        • Allison G.R.
        • Armstrong W.B.
        • Krugman M.E.
        • Strelzow V.V.
        • Kelly T.
        • Brugman J.J.
        • Hoerauf P.
        • McMicken B.L.
        Functional hemitongue reconstruction with the microvascular ulnar forearm flap.
        Plast Reconstr Surg. 1999; 104: 654-660
        • Tarsitano A.
        • Vietti M.V.
        • Cipriani R.
        • Marchetti C.
        Functional results of microvascular reconstruction after hemiglossectomy: free anterolateral thigh flap versus free forearm flap.
        Acta Otorhinolaryngol Ital. 2013; 33: 374-379
        • Grandis J.R.
        • Tweardy D.J.
        Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.
        Cancer Res. 1993; 53: 3579-3584
        • van Keulen S.
        • Nishio N.
        • Birkeland A.
        • Fakurnejad S.
        • Martin B.
        • Forouzanfar T.
        • Cunanan K.
        • Colevas A.D.
        • van den Berg S.
        • Rosenthal N.
        E. The sentinel margin: intraoperative ex vivo specimen mapping using relative fluorescence intensity.
        Clin Cancer Res. 2019; 25: 4656-4662
        • Krishnan G.
        • van den Berg N.S.
        • Nishio N.
        • Kapoor S.
        • Pei J.
        • Freeman L.
        • Lee Y.J.
        • Zhou Q.
        • van Keulen S.
        • Farkurnejad S.
        • Condon J.
        • Baik F.M.
        • Martin B.A.
        • Rosenthal E.L.
        Fluorescent molecular imaging can improve intraoperative sentinel margin detection in oral squamous cell carcinoma.
        J Nucl Med. 2022; 63: 1162-1168
        • Fakurnejad S.
        • Krishnan G.
        • van Keulen S.
        • Nishio N.
        • Birkeland A.C.
        • Baik F.M.
        • Kaplan M.J.
        • Colevas A.D.
        • van den Berg N.S.
        • Rosenthal E.L.
        • Martin B.A.
        Intraoperative molecular imaging for ex vivo assessment of peripheral margins in oral squamous cell carcinoma.
        Front Oncol. 2020; 91476
        • Ojo B.
        • Genden E.M.
        • Teng M.S.
        • Milbury K.
        • Misiukiewicz K.J.
        • Badr H.
        A systematic review of head and neck cancer quality of life assessment instruments.
        Oral Oncol. 2012; 48: 923-937