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Large cell neuroendocrine carcinoma of the floor of mouth and retromolar trigone in association with basaloid squamous cell carcinoma

      Abstract

      Large cell neuroendocrine carcinoma and basaloid squamous cell carcinoma are each rare but aggressive diseases of the head and neck. A case of large cell neuroendocrine carcinoma occurring simultaneously with a basaloid squamous cell carcinoma originating from the oral cavity is described in this report. The diagnosis of these pathologies can be challenging but is important, as staging and treatment recommendations differ from those for oral cavity squamous cell carcinoma.

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      References

        • Kusafuka K.
        • Asano R.
        • Kamijo T.
        • Iida Y.
        • Onitsuka T.
        • Kameya T.
        • Nakajima T.
        Large cell neuroendocrine carcinoma of the tongue base: case report of an unusual location with immunohistochemical analysis.
        Int J Oral Maxillofac Surg. 2009; 38: 296-299
        • Krishnamurthy A.
        • Vaidhyanathan A.
        • Majhi U.
        Large cell neuroendocrine carcinoma of the retromolar trigone.
        J Cancer Res Ther. 2011; 7: 343-346
        • Esmati E.
        • Babaei M.
        • Matini A.
        • Ashtiani M.S.
        • Hamed E.A.
        • Nosrati H.
        • Razi F.
        • Ganjalikhani M.
        Neuroendocrine carcinoma of the tongue.
        J Cancer Res Ther. 2015; 11: 659
        • Jiang S.X.
        • Kameya T.
        • Shoji M.
        • Dobashi Y.
        • Shinada J.
        • Yoshimura H.
        Large cell neuroendocrine carcinoma of the lung: a histologic and immunohistochemical study of 22 cases.
        Am J Surg Pathol. 1998; 22: 526-537
        • Barker Jr, J.L.
        • Glisson B.S.
        • Garden A.S.
        • El-Naggar A.K.
        • Morrison W.H.
        • Ang K.K.
        • Chao K.S.
        • Clayman G.
        • Rosenthal D.I.
        Management of nonsinonasal neuroendocrine carcinomas of the head and neck.
        Cancer. 2003; 98: 2322-2328
        • Mills S.E.
        Neuroectodermal neoplasms of the head and neck with emphasis on neuroendocrine carcinomas.
        Mod Pathol. 2002; 15: 264-278
        • Taggar A.S.
        • Simpson R.
        • Hao D.
        • Webster M.
        • Khalil M.
        • Lysack J.
        • Skarsgard D.
        Secondary neuroendocrine carcinoma following high-dose radiotherapy for head and neck cancer: report of two cases.
        Cureus. 2016; 8e847
        • de Sampaio Góes F.C.
        • Oliveira D.T.
        • Dorta R.G.
        • Nishimoto I.N.
        • Landman G.
        • Kowalski L.P.
        Prognoses of oral basaloid squamous cell carcinoma and squamous cell carcinoma: a comparison.
        Arch Otolaryngol Head Neck Surg. 2004; 130: 83-86
        • Yu G.Y.
        • Gao Y.
        • Peng X.
        • Chen Y.
        • Zhao F.Y.
        • Wu M.J.
        A clinicopathologic study on basaloid squamous cell carcinoma in the oral and maxillofacial region.
        Int J Oral Maxillofac Surg. 2008; 37: 1003-1008
        • Fritsch V.A.
        • Lentsch E.J.
        Basaloid squamous cell carcinoma of the larynx: analysis of 145 cases with comparison to conventional squamous cell carcinoma.
        Head Neck. 2014; 36: 164-170
        • Wang S.
        • Fang H.
        • Tong W.
        • Wang H.
        • Teng B.
        Coexistence of basaloid squamous cell carcinoma and large cell neuroendocrine carcinoma in the larynx: a case report and literature review.
        Ear Nose Throat J. 2020; (145561320956479)