Background and Objectives: There are two concerns in mandibular distraction osteogenesis (DO): the rather long
period of treatment and inferior alveolar nerve (IAN) injury. Nerve growth factor
(NGF) plays an important role in enhancement recovery of nerve injury and improvement
of new bone growth. In this study, we aimed to evaluate the effects of human NGF beta
delivery via a collagen/nano-hydroxyapatite/k-carrageenan gel to new bone growth and
inferior alveolar nerve histology in the rabbit model of mandibular distraction osteogenesis.
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© 2009 Published by Elsevier Inc.
