International Journal of Oral & Maxillofacial Surgery
Volume 41, Issue 1 , Pages 2-4 , January 2012

Platelet rich plasma for the prevention of osteoradionecrosis. A double blinded randomized cross over controlled trial

  • M.D. Batstone

      Affiliations

    • Maxillofacial Unit, Royal Brisbane Hospital, Herston 4029, QLD, Australia
    • Corresponding Author InformationAddress: Martin D. Batstone, Maxillofacial Unit, Royal Brisbane Hospital, Herston Road, Herston, QLD 4029, Australia. Tel: +61 0 407709907; Fax: +61 7 3636 3545.
    • ,
  • J. Cosson

      Affiliations

    • Maxillofacial Unit, Royal Brisbane Hospital, Herston 4029, QLD, Australia
    • ,
  • L. Marquart

      Affiliations

    • Statistics Unit, Royal Brisbane Hospital, Herston 4029, QLD, Australia
    • ,
  • C. Acton

      Affiliations

    • Maxillofacial Unit, Royal Brisbane Hospital, Herston 4029, QLD, Australia

,Accepted 13 June 2011.

References 

  1. Chang DT, Sandow PR, Morris CG, Hollander R, Scarborough L, Amdur RJ, et al. Do pre-irradiation dental extractions reduce the risk of osteoradionecrosis of the mandible?. Head Neck. 2007;29:528–536
  2. Delanian S, Lefaix JL. The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol. 2004;73:119–131
  3. Esposito M, Grusovin MG, Rees J, Karasoulos D, Felice P, Alissa R, et al. Effectiveness of sinus lift procedures for dental implant rehabilitation: a Cochrane systematic review. Eur J Oral Implantol. 2010;3:7–26
  4. Freymiller EG. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004;62:1047–10481046; author reply
  5. Freymiller EG, Aghaloo TL. Platelet-rich plasma: ready or not?. J Oral Maxillofac Surg. 2004;62:484–488
  6. Griffin XL, Smith CM, Costa ML. The clinical use of platelet-rich plasma in the promotion of bone healing: a systematic review. Injury. 2009;40:158–162
  7. Marx RE. A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg. 1983;41:351–357
  8. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Maxillofac Surg. 2004;62:489–496
  9. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet rich plasma: growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85:638–646
  10. Mendenhall WM, Mandibular osteoradionecrosis. J Clin Oncol. 2004;22:4867–4868
  11. Por YC, Shi L, Samuel M, Song C, Yeow VK. Use of tissue sealants in face-lifts: a metaanalysis. Aesthetic Plast Surg. 2009;33:336–339
  12. Sanchez AR, Sheridan PJ, Kupp LI. Is platelet-rich plasma the perfect enhancement factor? A current review. Int J Oral Maxillofac Implants. 2003;18:93–103
  13. Wahl MJ. Osteoradionecrosis prevention myths. Int J Radiat Oncol Biol Phys. 2006;64:661–669

☆ This study was presented at the Australian and New Zealand Head and Neck Cancer Society Meeting in Sydney, September 2010.

PII: S0901-5027(11)00255-4

doi: 10.1016/j.ijom.2011.06.018

International Journal of Oral & Maxillofacial Surgery
Volume 41, Issue 1 , Pages 2-4 , January 2012

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