International Journal of Oral & Maxillofacial Surgery
Volume 39, Issue 5 , Pages 469-477 , May 2010

The repair of critical-size defects with porous hydroxyapatite/polyamide nanocomposite: an experimental study in rabbit mandibles

  • J.C. Zhang

      Affiliations

    • State Key Laboratory of Oral Diseases, Sichuan University, China
    • West China College of Stomatology, Sichuan University, Chengdu, China
  • ,
  • H.Y. Lu

      Affiliations

    • State Key Laboratory of Oral Diseases, Sichuan University, China
    • West China College of Stomatology, Sichuan University, Chengdu, China
  • ,
  • G.Y. Lv

      Affiliations

    • Sichuan Guona Technology Co., Chengdu, China
  • ,
  • A.C. Mo

      Affiliations

    • State Key Laboratory of Oral Diseases, Sichuan University, China
    • West China College of Stomatology, Sichuan University, Chengdu, China
    • Corresponding Author InformationAddress: Anchun Mo, West China College of Stomatology, Sichuan University, No. 14, Sec. 3, Renmin Road, Chengdu 610041, China. Tel: +86 28 85503563; Fax: +86 28 85503630.
  • ,
  • Y.G. Yan

      Affiliations

    • Sichuan Guona Technology Co., Chengdu, China
  • ,
  • C. Huang

      Affiliations

    • State Key Laboratory of Oral Diseases, Sichuan University, China

,Accepted 12 January 2010.

References 

  1. Bruder SP, Kurth AA, Shea M, Hayes WC, Jaiswal N, Kadiyala S. Bone regeneration by implantation of purified, culture-expanded human mesenchymal stem cells. J Orthop Res. 1998;16:155–162
  2. David D. Histomorphometric Analysis of Bone Remodeling. Principles of Bone Biology. Third Edition. San Diego, CA, USA: Academic Press; 2008;pp. 447–463
  3. El Deeb M, Roszkowski M. Hydroxyapatite granules and blocks as an extracranial augmenting material in Rhesus monkeys. J Oral Maxillofac Surg. 1988;46:33–40
  4. Frisch T, Sorensen MS, Overgaard S, Lind M, Bretlau P. Volume-referent bone turnover estimated from the interlabel area fraction after sequential labeling. Bone. 1998;22:677–682
  5. Gauthier O, Bouler JM, Aguado E, Pilet P, Daculsi G. Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth. Biomaterials. 1998;19:133–139
  6. Giesen EBW, Ding M, Dalstra M, van Eijden TMGJ. Reduced mechanical load decreases the density, stiffness, and strength of cancellous bone of the mandibular condyle. Clin Biomech. 2003;18:358–363
  7. Goldberg , Stevenson S. The biology of bone grafts. Semin Arthroplasty. 1993;4:58–63
  8. Hench LL, Wilson J. An Introduction to Bioceramics. Singapore: World Scientific; 1993;
  9. Hsu YH, Turner IG, Miles AW. Fabrication of porous calcium phosphate bioceramics as synthetic cortical bone graft. J Bone Joint Surg. 2006;88-B:379
  10. Jorge GA, Ruth GL, Antonio SJ, Jesús R, Antonio BLL, Raúl GA, et al. The in vivo performance of a sol-gel glass and a glass-ceramic in the treatment of limited bone defects. Biomaterials. 2004;25:4639–4645
  11. Lane JM, Tomin E, Bostrom MP. Biosynthetic bone grafting. Clin Orthop Rel Res. 1999;367S:107–117
  12. Lee SI, Chun BC. Mechanical properties and fracture morphologies of poly (phenylene sulfide)/nylon66 blends-effect of nylon66 content and testing temperature. J Mater Sci. 2000;35:1187–1193
  13. Lu M, Rabie ABM. Microarchitecture of rabbit mandibular defects grafted with intramembranous or endochondral bone shown by micro-computed tomography. Br J Oral Maxillofac Surg. 2003;41:385–391
  14. Meng Y, Liu M, Wang SA, Mo AC, Huang C, Zuo Y, et al. Cellular reactions of osteoblast-like cells to a novel nanocomposite membrane for guided bone regeneration. Appl Surf Sci. 2000;255:267–269
  15. Schmitz JP, Hollinger JO. The critical size defect as an experimental model for craniomandibulofacial nonunions. Chin Orthop Rel Res. 1986;205:299–308
  16. Shors EC. Coralline bone graft substitutes. Orthop Clin North Am. 1999;30:599–613
  17. Sopyana I, Melb M, Rameshc S, Khalid KA. Porous hydroxyapatite for artificial bone applications. Sci Technol Adv Mater. 2007;8:116–123
  18. Springer ING, Fleiner B, Jepsen S, Acil Y. Culture of cells gained from temporomandibular joint cartilage on non-absorbable scaffolds. Biomaterials. 2001;22:2569–2577
  19. Tencer AF, Woodard PL, Swenson J, Brown KL. Mechanical and bone ingrowth properties of a polymer-coated, porous, synthetic, coralline hydroxyapatite bone-graft material. Ann N Y Acad Sci. 1988;523:157
  20. Ueno T, Kagawa T, Ishida N, Fukunaga J, Mizukawa N, Sugahara T, et al. Prefabricated bone graft induced from grafted periosteum for the repair of jaw defects: an experimental study in rabbits. J Craniomaxillofac Surg. 2001;29:219–223
  21. Wang HN, Li YB, Zuo Y, Li JH, Ma SS, Cheng L. Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering. Biomaterials. 2007;28:3338–3348
  22. Woodard JR, Hilldore AJ, Lan SK, Park CJ, Morgan AW, Eurell JA, et al. The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity. Biomaterials. 2007;28:45–54
  23. Zuo Y, Li YB, Li JD, Zhang X, Liao HB, Wang YY, et al. Novel bio-composite of hydroxyapatite reinforced polyamide and polyethylene: Composition and properties. Mater Sci Eng A. 2007;452–453:512–517

PII: S0901-5027(10)00016-0

doi: 10.1016/j.ijom.2010.01.013

International Journal of Oral & Maxillofacial Surgery
Volume 39, Issue 5 , Pages 469-477 , May 2010