International Journal of Oral & Maxillofacial Surgery
Volume 39, Issue 5 , Pages 486-492 , May 2010

Colorimetric analysis of unstained lesions surrounding oral squamous cell carcinomas and oral potentially malignant disorders using iodine

  • K. Maeda

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction
    • Corresponding Author InformationAddress: Keiko Maeda, Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan 113-8549, Tel.: +81 (3) 5803 5500; Fax: +81 (3) 5803 0298.
  • ,
  • T. Suzuki

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction
  • ,
  • Y. Ooyama

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction
  • ,
  • K. Nakakuki

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction
  • ,
  • M. Yamashiro

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction
  • ,
  • N. Okada

      Affiliations

    • Diagnostic Oral Pathology, Oral Restitution, Oral Health Science, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, Japan
  • ,
  • T. Amagasa

      Affiliations

    • Maxillofacial Surgery, Maxillofacial Reconstruction and Function, Division of Maxillofacial and Neck Reconstruction

,Accepted 2 November 2009.

References 

  1. Ashrafian H. Cancer's sweet tooth: the Janus effect of glucose metabolism in tumorigenesis. Lancet. 2006;367:618–621
  2. Basolo F, Ugolini C, Proietti A, Iacconi P, Berti P, Miccoli P. Role of frozen section associated with intraoperative cytology in comparison to FNA and FS alone in the management of thyroid nodules. Eur J Surg Oncol. 2007;33:769–775
  3. Black C, Marotti J, Zarovnaya E, Paydarfar J. Critical evaluation of frozen section margins in head and neck cancer resections. Cancer. 2006;107:2792–2800
  4. Brandwein-Gensler M, Teixeira MS, Lewis CM, Lee B, Rolnitzky L, Hille JJ, et al. Oral squamous cell carcinoma: histologic risk assessment, but not margin status, is strongly predictive of local disease-free and overall survival. Am J Surg Pathol. 2005;29:167–178
  5. Costello LC, Franklin RB. ‘Why do tumour cells glycolyse?’: from glycolysis through citrate to lipogenesis. Mol Cell Biochem. 2005;280:1–8
  6. Cox C, Centeno B, Dickson D, Clark J, Nicosia S, Dupont E, et al. Accuracy of intraoperative imprint cytology for sentinel lymph node evaluation in the treatment of breast carcinoma. Cancer. 2005;105:13–20
  7. Dawsey SM, Fleischer DE, Wang GQ, Zhou B, Kidwell JA, Lu N, et al. Mucosal iodine staining improves endoscopic visualization of squamous dysplasia and squamous cell carcinoma of the esophagus in Linxian, China. Cancer. 1998;83:220–231
  8. Du GF, Li CZ, Chen HZ, Chen XM, Xiao Q, Cao ZG, et al. Rose bengal staining in detection of oral precancerous and malignant lesions with colorimetric evaluation: a pilot study. Int J Cancer. 2007;120:1958–1963
  9. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med. 2001;345:1890–1900
  10. Freitag CP, Barros SG, Kruel CD, Putten AC, Dietz J, Gruber AC, et al. Esophageal dysplasias are detected by endoscopy with Lugol in patients at risk for squamous cell carcinoma in southern Brazil. Dis Esophagus. 1999;12:191–195
  11. Gatenby RA, Gillies RJ. Why do cancers have high aerobic glycolysis?. Nat Rev Cancer. 2004;4:891–899
  12. Hunt RWG. Measuring Colour. Third ed.. Kingston-upon-Thames, England: Fountain Press; 1998;p. 53–72
  13. Ina H, Shibuya H, Ohashi I, Kitagawa M. The frequency of a concomitant early esophageal cancer in male patients with oral and oropharyngeal cancer. Cancer. 1994;73:2038–2041
  14. Ishihara R, Yamada T, Iishi H, Kato M, Yamamoto S, Yamamoto S, et al. Quantitative analysis of the color change after iodine staining for diagnosing esophageal high-grade intraepithelial neoplasia and invasive cancer. Gastrointest Endosc. 2009;69:213–218
  15. Kerawara CJ, Beale V, Reed M. The role of vital tissue staining in the marginal control of oral squamous cell carcinoma. Int J Oral and Maxillofac Surg. 1999;29:32–35
  16. Koksal T, Dikbas I. Color stability of different denture teeth materials against various staining agents. Dent Mater J. 2008;27:139–144
  17. Nakanishi Y, Ochiai A, Yoshimura K. The clinicopathologic Significance of Small Areas Unstained by Lugol's Iodine in the Mucosa Surrounding Resected Esophageal Carcinoma. Cancer. 1998;82:1454–1459
  18. Nanci A. Ten Cate's Oral Histology – Development, Structure, and Function. 7th ed.. Philadelphia: Mosby; 2008;p. 53–72
  19. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55:74–108
  20. Pathak KA, Nason RW, Penner C, Viallet NR, Sutherland D, Kerr PD. Impact of use of frozen section assessment of operative margins on survival in oral cancer. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:235–239
  21. Petti S. Pooled estimate of world leukoplakia prevalence: a systematic review. Oral Oncol. 2003;39:770–780
  22. Pindborg JJ, Reichart PA, Smith CJ, Van der Waal I. World Health Organization International Histological Classification of Tumours. Histological typing of cancer and precancer of the oral mucosa. Berlin: Splinger; 1997;p. 11–33
  23. Schiller W. Early diagnosis of carcinoma of the cervix. Surg Gynecol Obstet. 1933;56:210–222
  24. Sedjo RL, Byers T, Barrera E, Cohen C, Fontham ET, Newman LA, et al. A midpoint assessment of the American Cancer Society challenge goal to decrease cancer incidence by 25% between 1992 and 2015. CA Cancer J Clin. 2007;57:326–340
  25. Seghi RR, Hewlett ER, Kim J. Visual and instrumental colorimetric assessments of small color differences on translucent dental porcelain. J Dent Res. 1989;68:1760–1764
  26. Shimizu Y, Tsukagoshi H, Fujita M, Hosokawa M, Kato M, Asaka M. Endoscopic screening for early esophageal cancer by iodine staining in patients with other current or prior primary cancers. Gastrointest Endosc. 2001;53:1–5
  27. Shiozaki H, Yano H, Yano T, Nishiyama K. Endoscopic screening of early esophageal cancer with the Lugol dye method in patients with head and neck cancers. Cancer. 1990;66:2068–2071
  28. Sobin LH, Wittekind C. TMN classification of Malignant Tumors. New York: John Wiley & Sons; 2002;p. 19–26
  29. Tincani AJ, Brandalise N, Altemani A, Scanavini RC, Valério JB, Lage HT, et al. Diagnosis of superficial esophageal cancer and dysplasia using endoscopic screening with a 2% Lugol dye solution in patients with head and neck cancer. Head Neck. 2000;22:170–174
  30. Voegeli R. Schiller's iodine test in the diagnosis of esophageal disease. Preliminary report. Pract Otorhinolaryngol. 1966;28:230–239
  31. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36:575–580
  32. Yamashiro M. A study on colorimetry of oral mucosal lesions. J Stmatol. Jpn. 1996;63:194–213(in Japanese)
  33. Yokoo K, Noma H, Inoue T, Hashimoto S, Shimono M. Cell proliferation and tumour suppressor gene expression in iodine unstained area surrounding oral squamous cell carcinoma. Int J Oral Maxillofac Surg. 2004;33:75–83

PII: S0901-5027(09)01147-3

doi: 10.1016/j.ijom.2009.11.001

International Journal of Oral & Maxillofacial Surgery
Volume 39, Issue 5 , Pages 486-492 , May 2010